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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Plasmid-mediated resistance ： ウィキペディア英語版 Plasmid-mediated resistance Plasmid-mediated resistance is the transfer of antimicrobial-resistant coding genes which are carried on plasmids. The plasmids can be transferred between prokaryotes through horizontal gene transfer. The spread of multiple antimicrobial resistance has been enhanced by selective pressure from human and veterinary medicine. ==ESBL Enterbacteriaceae== Plasmid encoded beta-lactamase is responsible for the emergence of resistant strains of Enterobacteriaceae. These enzymes are collectively termed as Extended Spectrum Beta Lactamases (ESBL). They are especially problematic because strains that produce them may appear to be susceptible to the third generation cephalosporins but are in fact resistant to these antibiotics.These beta-lactamases degrade all the beta-lactam antibiotics except carbapenems and sometimes beta-lactam/beta-lactamase inhibitor combinations (e.g.-Piperacillin/Tazobactam.) In addition, since the plasmids that carry ESBL genes also commonly encode resistance determinants for many other antibiotics, ESBL strains are often resistant to many non-beta-lactam antibiotics as well 〔 Broad spectrum antibiotics and resistance in non-target bacteria: an example from tetracycline, Journal of Pure and Applied Microbiology, (2014); 8(4): 2667-2671. 〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Plasmid-mediated resistance」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.